Active Studies

We are constantly seeking participants for a number of studies. Please apply to any studies for which you may qualify, or call us at (417) 883-7889 for more information!

    Alder-015

    Dr. True and Clinvest are seeking volunteers with migraine. This study evaluates the effectiveness of the study drug during a migraine attack. Qualified volunteers will be randomly assigned to receive a study drug or a matching placebo. The total duration of the study will last up to approximately 12 weeks and up to three clinic visits. Your first appointment will last approximately two hours. Once you experience a qualifying migraine, you will come in for your second appointment within six hours after the start of the migraine. This visit will last approximately six hours. The study drug will be administered by IV. Study drug and all study-related procedures will be provided at no cost to you (including basic study-related physical exams, bloodwork, ECG’s, and urine drug/pregnancy tests). Compensation will be provided for qualified participants.

    TCH-006

    This study is a chronic migraine study for ages 18-75 using a neuromodulator device on your upper arm. This device will sync via Bluetooth to a smartphone, which will control the device, as well as the location of headache diary. A total of up to 4 visits spanning no longer than 4 months with a 1-month baseline period and up to 3-months open-label period. Compensation may be provided for time and travel.

    STS101-002

    Clinvest is seeking volunteers with migraine. This study is evaluating the safety and effectiveness of STS101, a dihydroergotamine (DHE) dry powder formulation in a single-use nasal device that is being developed for the treatment of migraine. Qualified volunteers will treat one migraine attack and be randomly assigned to receive a device containing a single dose of study medication STS101 in one of two different doses or a matching placebo. The total duration of the study will be last up to approximately 12 weeks. Your first appointment would last approximately 2 hours with follow-up visits lasting around 1 hour. Study medication would be provided, as well as all study-related procedures, at no cost to you (including basic study-related physical exams, bloodwork, ECG’s, and urine drug/pregnancy tests). Compensation will be provided for your time and travel.

    Abbvie M16-852

    Eligible subjects over 50 years in age who have been newly diagnosed or have relapsing Giant Cell Arteritis. Participants will be randomized to receive either standard of care or investigational product in addition to standard of care for up to two years over 21 visits. Your first appointment would last approximately 2 hours. If you qualify and choose to volunteer, we would provide investigational study pills, or standard of care pills and all study-related procedures at no cost to you (including basic study-related physical exams, bloodwork, ECG’s, and urine drug/pregnancy tests). Compensation may be provided for your time and travel.

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